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3GN0

Crystal structure of human arginase I in complex with difluoromethylornithine (DFMO)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Arginase-1polymer32234779.92UniProt (P05089)
Pfam (PF00491)
Homo sapiens (human)Type I arginase, Liver-type arginase
2C, D, F, G
(A, B)
MANGANESE (II) IONnon-polymer54.94Chemie (MN)
3E, H
(A, B)
ALPHA-DIFLUOROMETHYLORNITHINEnon-polymer182.22Chemie (DMO)
4I, J
(A, B)
waterwater18.0345Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight69559.8
Non-Polymers*Number of molecules6
Total formula weight584.1
All*Total formula weight70143.8
*Water molecules are not included.

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PDB entries from 2024-12-18

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