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3GM1

Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2 in Complex with Paxillin LD4 Motif-Derived Peptides

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D
(A, B)
Protein tyrosine kinase 2 betapolymer15316692.22UniProt (Q14289)
Pfam (PF03623)
Homo sapiens (Human)
2B, C, E, F
(E, F, C, D)
Paxillinpolymer131436.64UniProt (P49023)
3G, H, I, J
(A, B, C, D)
waterwater18.017Chemie (HOH)
Sequence modifications
A, B: 861 - 1009 (UniProt: Q14289)
PDBExternal DatabaseDetails
Gly 857-expression tag
Ser 858-expression tag
His 859-expression tag
Met 860-expression tag
Ala 899Cys 899engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight39130.8
All*Total formula weight39130.8
*Water molecules are not included.

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PDB entries from 2025-12-17

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