3GLT
Crystal Structure of Human SIRT3 with ADPR bound to the AceCS2 peptide containing a thioacetyl lysine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NAD-dependent deacetylase sirtuin-3, mitochondrial | polymer | 285 | 31612.3 | 1 | UniProt (Q9NTG7) Pfam (PF02146) | Homo sapiens (human) | SIR2-like protein 3, hSIRT3 |
| 2 | B (B) | Acetyl-coenzyme A synthetase 2-like, mitochondrial | polymer | 12 | 2076.2 | 1 | UniProt (Q9NUB1) | Homo sapiens | Acetate--CoA ligase 2, Acetyl-CoA synthetase 2, Acyl-CoA synthetase short-chain family member 1 |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (A) | CARBONATE ION | non-polymer | 60.0 | 1 | Chemie (CO3) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A: 118 - 399 (UniProt: Q9NTG7)
| PDB | External Database | Details |
|---|---|---|
| Ser 115 | - | expression tag |
| Asn 116 | - | expression tag |
| Ala 117 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33688.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 221.5 | |
| All* | Total formula weight | 33910.1 |
