3GKI
NPC1(NTD):cholesterol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Niemann-Pick C1 protein | polymer | 232 | 25738.9 | 1 | UniProt (O15118) Pfam (PF16414) | Homo sapiens (human) | |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) | |||
| 5 | E (A) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 23 - 252 (UniProt: O15118)
| PDB | External Database | Details |
|---|---|---|
| Gly 21 | - | expression tag |
| Ala 22 | - | expression tag |
| Gln 70 | Asn 70 | engineered mutation |
| Gln 122 | Asn 122 | engineered mutation |
| Gln 185 | Asn 185 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25738.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 607.9 | |
| All* | Total formula weight | 26771.2 |
