3GJW
PARP complexed with A968427
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Poly [ADP-ribose] polymerase 1 | polymer | 350 | 39168.8 | 1 | UniProt (P09874) Pfam (PF02877) Pfam (PF00644) | Homo sapiens (human) | PARP-1, ADPRT, NAD(+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthetase 1 |
| 2 | B (A) | 7-(pyrrolidin-1-ylmethyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one | non-polymer | 267.3 | 1 | Chemie (GJW) | |||
| 3 | C (A) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 1 - 350 (UniProt: P09874)
| PDB | External Database | Details |
|---|---|---|
| Ala 101 | Val 762 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39168.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 267.3 | |
| All* | Total formula weight | 39436.1 |
