3GJS

Caspase-3 Binds Diverse P4 Residues in Peptides

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Caspase-3 subunit p17	polymer	147	16639.9	2	UniProt (P42574) Pfam (PF00656)	Homo sapiens (human)	CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Yama protein, SREBP cleavage activity 1, SCA-1, Caspase-3 subunit p17, Caspase-3 subunit p12
2	B, D (B, D)	Caspase-3 subunit p12	polymer	108	12739.5	2	UniProt (P42574) Pfam (PF00656)	Homo sapiens (human)	CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Yama protein, SREBP cleavage activity 1, SCA-1, Caspase-3 subunit p17, Caspase-3 subunit p12
3	E, F (E, F)	Ac-YVAD-Cho inhibitor	polymer	5	478.5	2
4	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	270	Chemie (HOH)

Sequence modifications

B, D: 176 - 277 (UniProt: P42574)

PDB	External Database	Details
His 278	-	expression tag
His 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	59715.9
All*	Total formula weight	59715.9

*Water molecules are not included.