3GJ6
Crystal structure of human RanGDP-Nup153ZnF1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GTP-binding nuclear protein Ran | polymer | 221 | 24846.5 | 1 | UniProt (P62826) Pfam (PF00071) | Homo sapiens (human) | GTPase Ran, Ras-related nuclear protein, Ras-like protein TC4, Androgen receptor-associated protein 24 |
| 2 | B (B) | Nuclear pore complex protein Nup153 | polymer | 34 | 3528.0 | 1 | UniProt (P49791) Pfam (PF00641) | Rattus norvegicus (rat) | Nucleoporin Nup153, 153 kDa nucleoporin |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 5 | E (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A: 2 - 216 (UniProt: P62826)
B: 658 - 686 (UniProt: P49791)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| His -2 | - | expression tag |
| Met -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Ser 35 | Phe 35 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 653 | - | expression tag |
| Pro 654 | - | expression tag |
| Leu 655 | - | expression tag |
| Gly 656 | - | expression tag |
| Ser 657 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28374.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 532.9 | |
| All* | Total formula weight | 28907.4 |
