3GJ6

Crystal structure of human RanGDP-Nup153ZnF1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	GTP-binding nuclear protein Ran	polymer	221	24846.5	1	UniProt (P62826) Pfam (PF00071) In PDB	Homo sapiens (human)	GTPase Ran, Ras-related nuclear protein, Ras-like protein TC4, Androgen receptor-associated protein 24
2	B	Nuclear pore complex protein Nup153	polymer	34	3528.0	1	UniProt (P49791) Pfam (PF00641) In PDB	Rattus norvegicus (rat)	Nucleoporin Nup153, 153 kDa nucleoporin
3	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	A	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
5	B	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
6		water	water		18.0	34	Chemie (HOH)

Sequence modifications

A: 2 - 216 (UniProt: P62826)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
His -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag
Ser 1	-	expression tag
Ser 35	Phe 35	engineered mutation

B: 658 - 686 (UniProt: P49791)

PDB	External Database	Details
Gly 653	-	expression tag
Pro 654	-	expression tag
Leu 655	-	expression tag
Gly 656	-	expression tag
Ser 657	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28374.5
Non-Polymers*	Number of molecules	3
	Total formula weight	532.9
All*	Total formula weight	28907.4

*Water molecules are not included.