3GJ3

Crystal structure of human RanGDP-Nup153ZnF2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	GTP-binding nuclear protein Ran	polymer	221	24906.6	1	UniProt (P62826) Pfam (PF00071)	Homo sapiens (human)	GTPase Ran, Ras-related nuclear protein, Ras-like protein TC4, Androgen receptor-associated protein 24
2	B (B)	Nuclear pore complex protein Nup153	polymer	33	3407.9	1	UniProt (P49791) Pfam (PF00641)	Rattus norvegicus (rat)	Nucleoporin Nup153, 153 kDa nucleoporin
3	C (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	D (A)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
5	E (B)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
6	F, G (A, B)	water	water		18.0	250	Chemie (HOH)

Sequence modifications

A: 2 - 216 (UniProt: P62826)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
His -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag
Ser 1	-	expression tag

B: 723 - 750 (UniProt: P49791)

PDB	External Database	Details
Gly 718	-	expression tag
Pro 719	-	expression tag
Leu 720	-	expression tag
Gly 721	-	expression tag
Ser 722	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	28314.5
Non-Polymers*	Number of molecules	3
	Total formula weight	532.9
All*	Total formula weight	28847.4

*Water molecules are not included.