3GIN

Crystal structure of E454K-CBD1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Sodium/calcium exchanger 1	polymer	160	17462.2	2	UniProt (P23685) Pfam (PF03160)	Canis lupus familiaris (dog)	Na(+)/Ca(2+)-exchange protein 1
2	C, D, E, F, G... (A, B)	CALCIUM ION	non-polymer		40.1	7	Chemie (CA)
3	J, K (A, B)	water	water		18.0	98	Chemie (HOH)

Sequence modifications

A, B: 370 - 509 (UniProt: P23685)

PDB	External Database	Details
Met 350	-	expression tag
Ala 351	-	expression tag
His 352	-	expression tag
His 353	-	expression tag
His 354	-	expression tag
His 355	-	expression tag
His 356	-	expression tag
His 357	-	expression tag
Ser 358	-	expression tag
Ala 359	-	expression tag
Ala 360	-	expression tag
Leu 361	-	expression tag
Glu 362	-	expression tag
Val 363	-	expression tag
Leu 364	-	expression tag
Phe 365	-	expression tag
Gln 366	-	expression tag
Gly 367	-	expression tag
Pro 368	-	expression tag
Gly 369	-	expression tag
Lys 454	Glu 486	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34924.4
Non-Polymers*	Number of molecules	7
	Total formula weight	280.5
All*	Total formula weight	35204.9

*Water molecules are not included.