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3GGF

Crystal structure of human Serine/threonine-protein kinase MST4 in complex with an quinazolin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Serine/threonine-protein kinase MST4polymer30133860.82UniProt (Q9P289)
Pfam (PF00069)
Homo sapiens (Human)Mammalian STE20-like protein kinase 4, STE20-like kinase MST4, MST-4, Serine/threonine-protein kinase MASK, Mst3 and SOK1-related kinase
2C, D, E, F, H...
(A, B)
CADMIUM IONnon-polymer112.47Chemie (CD)
3G, K
(A, B)
[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILEnon-polymer381.42Chemie (GVD)
4L, M
(A, B)
waterwater18.0146Chemie (HOH)
Sequence modifications
A, B: 1 - 300 (UniProt: Q9P289)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight67721.5
Non-Polymers*Number of molecules9
Total formula weight1549.7
All*Total formula weight69271.3
*Water molecules are not included.

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PDB entries from 2024-11-06

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