3GG2

Crystal structure of UDP-glucose 6-dehydrogenase from Porphyromonas gingivalis bound to product UDP-glucuronate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family	polymer	450	49921.0	4	UniProt (Q7MVC7) Pfam (PF03721) Pfam (PF00984) Pfam (PF03720)	Porphyromonas gingivalis (Bacteroides gingivalis)
2	E, F, G, H, I... (A, B, C, D)	URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID	non-polymer		580.3	6	Chemie (UGA)
3	K, L, M, N (A, B, C, D)	water	water		18.0	1307	Chemie (HOH)

Sequence modifications

A, B, C, D: 80 - 518 (UniProt: Q7MVC7)

PDB	External Database	Details
Met 77	-	expression tag
Ser 78	-	expression tag
Leu 79	-	expression tag
Ile 158	Val 158	engineered mutation
Ser 175	Gly 175	engineered mutation
Ala 211	Val 211	engineered mutation
Ala 485	Thr 485	engineered mutation
Glu 519	-	expression tag
Gly 520	-	expression tag
His 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag
His 526	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	199684.2
Non-Polymers*	Number of molecules	6
	Total formula weight	3481.7
All*	Total formula weight	203165.9

*Water molecules are not included.