3GFT

Human K-Ras (Q61H) in complex with a GTP analogue

Replaces:  2PMX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	GTPase KRas	polymer	187	21482.2	6	UniProt (P01116) Pfam (PF00071) In PDB	Homo sapiens (human)	K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras
2	A, B, C, D, E...	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
3	A, B, C, D, E...	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	6	Chemie (GNP)
4	A	UNKNOWN ATOM OR ION	non-polymer			1	Chemie (UNX)
5	F	CITRIC ACID	non-polymer		192.1	1	Chemie (CIT)
6		water	water		18.0	142	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 169 (UniProt: P01116)

PDB	External Database	Details
Met -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Arg -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
His 61	Gln 61	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	128893.0
Non-Polymers*	Number of molecules	14
	Total formula weight	3471.1
All*	Total formula weight	132364.1

*Water molecules are not included.