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3GEP

Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Hypoxanthine-guanine phosphoribosyltransferasepolymer21724481.22UniProt (P00492)
Pfam (PF00156)
Homo sapiens (Human)HGPRTase, HGPRT
2C, D
(A, B)
{[(1S)-2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-1-(hydroxymethyl)ethoxy]methyl}phosphonic acidnon-polymer319.22Chemie (24H)
3E, F
(A, B)
waterwater18.0168Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight48962.4
Non-Polymers*Number of molecules2
Total formula weight638.4
All*Total formula weight49600.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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