3GEF
Crystal structure of the R482W mutant of lamin A/C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Lamin-A/C | polymer | 118 | 13094.6 | 4 | UniProt (P02545) Pfam (PF00932) | Homo sapiens (human) | 70 kDa lamin, Renal carcinoma antigen NY-REN-32 |
| 2 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 320 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 436 - 552 (UniProt: P02545)
| PDB | External Database | Details |
|---|---|---|
| Ser 435 | - | expression tag |
| Trp 482 | Arg 482 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 52378.5 | |
| All* | Total formula weight | 52378.5 |
