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3GBB

X-ray structure of iGluR5 ligand-binding core (S1S2) in complex with MSVIII-19 at 2.10A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Glutamate receptor, ionotropic kainate 1polymer25729108.52UniProt (P22756)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (rat)Glutamate receptor 5, GluR-5, GluR5
2C, D
(A, B)
(2R,3aR,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acidnon-polymer259.32Chemie (MS8)
3E, F
(A, B)
waterwater18.0346Chemie (HOH)
Sequence modifications
A, B: 2 - 116 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 1-expression tag
Gly 34Ala 462SEE REMARK 999
A, B: 119 - 257 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 117-linker
Thr 118-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight58216.9
Non-Polymers*Number of molecules2
Total formula weight518.5
All*Total formula weight58735.4
*Water molecules are not included.

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PDB entries from 2025-12-24

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