3GA3
Crystal structure of the C-terminal domain of human MDA5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interferon-induced helicase C domain-containing protein 1, MDA5 | polymer | 133 | 15588.2 | 1 | UniProt (Q9BYX4) Pfam (PF11648) | Homo sapiens (Human) | Interferon-induced with helicase C domain protein 1, Helicase with 2 CARD domains, Helicard, Melanoma differentiation-associated protein 5, MDA-5, RNA helicase-DEAD box protein 116, Murabutide down-regulated protein |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A: 893 - 1017 (UniProt: Q9BYX4)
| PDB | External Database | Details |
|---|---|---|
| Leu 1018 | - | expression tag |
| Glu 1019 | - | expression tag |
| His 1020 | - | expression tag |
| His 1021 | - | expression tag |
| His 1022 | - | expression tag |
| His 1023 | - | expression tag |
| His 1024 | - | expression tag |
| His 1025 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15588.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 15653.6 |
