3G8T
Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, B, C, D) | U1 small nuclear ribonucleoprotein A | polymer | 98 | 11340.3 | 4 | UniProt (P09012) Pfam (PF00076) | Homo sapiens (human) | U1 snRNP protein A, U1A protein, U1-A |
| 2 | B, E, H, K (E, F, G, H) | RNA (5'-R(*AP*(A2M)P*GP*CP*GP*CP*CP*AP*GP*AP*AP*CP*U)-3') | polymer | 13 | 4177.6 | 4 | syntetic construct | ||
| 3 | C, F, I, L (P, Q, R, S) | glmS glucosamine-6-phosphate activated ribozyme | polymer | 141 | 45608.9 | 4 | syntetic construct | ||
| 4 | M, R, V, Z (E, Q, R, H) | 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose | non-polymer | 259.2 | 4 | Chemie (GLP) PubChem (24961603) | |||
| 5 | N, O, P, Q, S... (P, F, Q, R) | MAGNESIUM ION | non-polymer | 24.3 | 10 | Chemie (MG) PubChem (888) | |||
| 6 | AA, BA, CA, DA, EA... (A, E, P, B, F...) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 98 (UniProt: P09012)
| PDB | External Database | Details |
|---|---|---|
| His 31 | Tyr 31 | engineered mutation |
| Arg 36 | Gln 36 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 244507.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1279.7 | |
| All* | Total formula weight | 245786.8 |
