3G84
Crystal structure of the trimeric neck and carbohydrate recognition domain of R343V mutant of human surfactant protein D in complex with alpha 1,2 dimannose.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Pulmonary surfactant-associated protein D | polymer | 160 | 17214.1 | 3 | UniProt (P35247) Pfam (PF09006) Pfam (PF00059) | Homo sapiens (man) | SP-D, PSP-D, Lung surfactant protein D |
| 2 | D, E, F (D, E, F) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose | branched | 342.3 | 3 | In PDB BIRD (PRD_900111) GlyTouCan (G53402KW) | 2alpha-alpha-mannobiose | ||
| 3 | G, H, I, J, K... (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 9 | Chemie (CA) | |||
| 4 | P, Q, R (A, B, C) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A, B, C: 203 - 355 (UniProt: P35247)
| PDB | External Database | Details |
|---|---|---|
| Ala 196 | - | expression tag |
| Met 197 | - | expression tag |
| Ala 198 | - | expression tag |
| Asp 199 | - | expression tag |
| Ile 200 | - | expression tag |
| Gly 201 | - | expression tag |
| Ser 202 | - | expression tag |
| Val 343 | Arg 363 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 51642.4 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1026.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 360.7 | |
| All* | Total formula weight | 53030.0 |
