Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3G6G

Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BProto-oncogene tyrosine-protein kinase Srcpolymer28632726.62UniProt (P00523)
Pfam (PF07714)
In PDB
Gallus gallus (chicken)pp60c-src, p60-Src, c-Src
2A, BN-{3-[(3-{4-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}pyridin-2-yl)amino]-4-methylphenyl}-4-[(4-methylpiperazin-1-yl)methyl]benzamidenon-polymer615.72Chemie (G6G)
3A, BGLYCEROLnon-polymer92.12Chemie (GOL)
4waterwater18.058Chemie (HOH)
Sequence modifications
A, B: 251 - 533 (UniProt: P00523)
PDBExternal DatabaseDetails
Gly 248-expression tag
His 249-expression tag
Met 250-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight65453.3
Non-Polymers*Number of molecules4
Total formula weight1415.6
All*Total formula weight66868.9
*Water molecules are not included.

222624

PDB entries from 2024-07-17

PDB statisticsPDBj update infoContact PDBjnumon