3G5I
Crystal Structure of the E.coli RihA pyrimidine nucleosidase bound to a iminoribitol-based inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyrimidine-specific ribonucleoside hydrolase rihA | polymer | 312 | 33866.7 | 4 | UniProt (P41409) Pfam (PF01156) | Escherichia coli | RihA/YbeK pyrimidine nucleoside hydrolase, Cytidine/uridine-specific hydrolase |
| 2 | E (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 3 | F, H, J, L (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | G, I, K, M (A, B, C, D) | (2S,3S,4R,5R)-2-(3,4-diaminophenyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol | non-polymer | 239.3 | 4 | Chemie (DNB) | |||
| 5 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 510 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 311 (UniProt: P41409)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 135466.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1195.5 | |
| All* | Total formula weight | 136662.4 |
