3G4S
Co-crystal structure of Tiamulin bound to the large ribosomal subunit
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (0) | 23S ribosomal RNA | polymer | 2923 | 946463.5 | 1 | GenBank (55229667) | Haloarcula marismortui | |
2 | B (A) | 50S ribosomal protein L2P | polymer | 237 | 24980.3 | 1 | UniProt (P20276) Pfam (PF00181) Pfam (PF03947) | Haloarcula marismortui | Hmal2, Hl4 |
3 | C (B) | 50S ribosomal protein L3P | polymer | 337 | 37265.2 | 1 | UniProt (P20279) Pfam (PF00297) | Haloarcula marismortui | Hmal3, Hl1 |
4 | D (C) | 50S ribosomal protein L4P | polymer | 246 | 26457.1 | 1 | UniProt (P12735) Pfam (PF00573) | Haloarcula marismortui | Hmal4, Hl6 |
5 | E (D) | 50S ribosomal protein L5P | polymer | 177 | 19551.7 | 1 | UniProt (P14124) Pfam (PF00281) Pfam (PF00673) | Haloarcula marismortui | Hmal5, Hl13 |
6 | F (E) | 50S ribosomal protein L6P | polymer | 172 | 19316.0 | 1 | UniProt (P14135) Pfam (PF00347) | Haloarcula marismortui | Hmal6, Hl10 |
7 | G (F) | 50S ribosomal protein L7Ae | polymer | 119 | 12660.7 | 1 | UniProt (P12743) Pfam (PF01248) | Haloarcula marismortui | Hs6 |
8 | H (G) | 50S ribosomal protein L10 | polymer | 348 | 37169.8 | 1 | UniProt (P15825) Pfam (PF00466) Pfam (PF17777) | Haloarcula marismortui | Ribosomal protein L10, Acidic ribosomal protein P0 homolog, L10E, HMal10 |
9 | I (H) | 50S ribosomal protein L10e | polymer | 177 | 19942.7 | 1 | UniProt (P60617) Pfam (PF00252) | Haloarcula marismortui | |
10 | J (I) | 50S ribosomal protein L11P | polymer | 70 | 7408.1 | 1 | UniProt (P14122) Pfam (PF00298) | Haloarcula marismortui | Hmal11 |
11 | K (J) | 50S ribosomal protein L13P | polymer | 142 | 15931.8 | 1 | UniProt (P29198) Pfam (PF00572) | Haloarcula marismortui | Hmal13 |
12 | L (K) | 50S ribosomal protein L14P | polymer | 132 | 14216.2 | 1 | UniProt (P22450) Pfam (PF00238) | Haloarcula marismortui | Hmal14, Hl27 |
13 | M (L) | 50S ribosomal protein L15P | polymer | 165 | 18005.4 | 1 | UniProt (P12737) Pfam (PF00828) | Haloarcula marismortui | Hmal15, Hl9 |
14 | N (M) | 50S ribosomal protein L15e | polymer | 194 | 22143.9 | 1 | UniProt (P60618) Pfam (PF00827) | Haloarcula marismortui | 50S ribosomal protein LC12 |
15 | O (N) | 50S ribosomal protein L18P | polymer | 186 | 20509.7 | 1 | UniProt (P14123) Pfam (PF17144) | Haloarcula marismortui | Hmal18, Hl12 |
16 | P (O) | 50S ribosomal protein L18e | polymer | 115 | 12307.7 | 1 | UniProt (P12733) Pfam (PF00828) | Haloarcula marismortui | Hl29, L19 |
17 | Q (P) | 50S ribosomal protein L19e | polymer | 143 | 16169.9 | 1 | UniProt (P14119) Pfam (PF01280) | Haloarcula marismortui | Hmal19, Hl24 |
18 | R (Q) | 50S ribosomal protein L21e | polymer | 95 | 10436.6 | 1 | UniProt (P12734) Pfam (PF01157) | Haloarcula marismortui | Hl31 |
19 | S (R) | 50S ribosomal protein L22P | polymer | 150 | 16363.3 | 1 | UniProt (P10970) Pfam (PF00237) | Haloarcula marismortui | Hmal22, Hl23 |
20 | T (S) | 50S ribosomal protein L23P | polymer | 81 | 9178.0 | 1 | UniProt (P12732) Pfam (PF00276) | Haloarcula marismortui | Hmal23, Hl25, L21 |
21 | U (T) | 50S ribosomal protein L24P | polymer | 119 | 13539.8 | 1 | UniProt (P10972) Pfam (PF16906) Pfam (PF00467) | Haloarcula marismortui | Hmal24, Hl16, Hl15 |
22 | V (U) | 50S ribosomal protein L24e | polymer | 53 | 5919.4 | 1 | UniProt (P14116) Pfam (PF01246) | Haloarcula marismortui | Hl21/Hl22 |
23 | W (V) | 50S ribosomal protein L29P | polymer | 65 | 7145.1 | 1 | UniProt (P10971) Pfam (PF00831) | Haloarcula marismortui | Hmal29, Hl33 |
24 | X (W) | 50S ribosomal protein L30P | polymer | 154 | 17062.9 | 1 | UniProt (P14121) Pfam (PF00327) | Haloarcula marismortui | Hmal30, Hl20, Hl16 |
25 | Y (X) | 50S ribosomal protein L31e | polymer | 82 | 9315.5 | 1 | UniProt (P18138) Pfam (PF01198) | Haloarcula marismortui | L34, Hl30 |
26 | Z (Y) | 50S ribosomal protein L32e | polymer | 142 | 16079.0 | 1 | UniProt (P12736) Pfam (PF01655) | Haloarcula marismortui | Hl5 |
27 | AA (Z) | 50S ribosomal protein L37Ae | polymer | 73 | 8224.1 | 1 | UniProt (P60619) Pfam (PF01780) | Haloarcula marismortui | |
28 | BA (1) | 50S ribosomal protein L37e | polymer | 56 | 6199.0 | 1 | UniProt (P32410) Pfam (PF01907) | Haloarcula marismortui | L35e |
29 | CA (2) | 50S ribosomal protein L39e | polymer | 50 | 6133.1 | 1 | UniProt (P22452) Pfam (PF00832) | Haloarcula marismortui | Hl39e, Hl46e |
30 | DA (3) | 50S ribosomal protein L44E | polymer | 92 | 10815.2 | 1 | UniProt (P32411) Pfam (PF00935) | Haloarcula marismortui | La, Hla |
31 | EA (9) | 5S ribosomal RNA | polymer | 122 | 39303.4 | 1 | GenBank (6468293) | Haloarcula marismortui | |
32 | AB, AC, AD, BB, BC... (0, B, T, C, Y...) | MAGNESIUM ION | non-polymer | 24.3 | 93 | Chemie (MG) | |||
33 | LD (0) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
34 | AE, AF, AL, BE, BF... (0, R, S, C, J...) | SODIUM ION | non-polymer | 23.0 | 75 | Chemie (NA) | |||
35 | AG, AK, BG, CG, CL... (0, A, R, B, Y...) | CHLORIDE ION | non-polymer | 35.5 | 22 | Chemie (CL) | |||
36 | AH, AI, AJ, BH, BI... (0, A, R, S, B...) | STRONTIUM ION | non-polymer | 87.6 | 108 | Chemie (SR) | |||
37 | XJ (0) | TIAMULIN | non-polymer | 493.7 | 1 | Chemie (MUL) | |||
38 | HL, KL, LL, PL, XK (U, Z, 1, 3, O) | CADMIUM ION | non-polymer | 112.4 | 5 | Chemie (CD) | |||
39 | AM, AN, BM, BN, CM... (B, 2, C, 3, D...) | water | water | 18.0 | 7822 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 31 |
Total formula weight | 1446214.1 | |
Non-Polymers* | Number of molecules | 305 |
Total formula weight | 15322.4 | |
All* | Total formula weight | 1461536.5 |