3G3I
Crystal structure of the GluR6 ligand binding domain dimer I442H K494E I749L Q753K mutant with glutamate and NaCl at 1.37 Angstrom resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glutamate receptor, ionotropic kainate 2 | polymer | 259 | 29397.6 | 2 | UniProt (P42260) Pfam (PF10613) Pfam (PF00060) In PDB | Rattus norvegicus | Glutamate receptor 6, GluR-6, GluR6 |
2 | A, B | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
4 | A, B | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
5 | water | water | 18.0 | 692 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 117 (UniProt: P42260)
A, B: 120 - 259 (UniProt: P42260)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
His 46 | Ile 473 | engineered mutation |
Glu 98 | Lys 525 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 118 | - | linker |
Thr 119 | - | linker |
Leu 233 | Ile 780 | engineered mutation |
Lys 237 | Gln 784 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 58795.2 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 398.7 | |
All* | Total formula weight | 59193.9 |