3G3H
Crystal structure of the GluR6 ligand binding domain dimer K665R I749L Q753K mutant with glutamate and NaCl at 1.5 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor, ionotropic kainate 2 | polymer | 259 | 29400.7 | 2 | UniProt (P42260) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus | Glutamate receptor 6, GluR-6, GluR6 |
| 2 | C, G (A, B) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
| 3 | D, H (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | E, F, I (A, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 710 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 117 (UniProt: P42260)
A, B: 120 - 259 (UniProt: P42260)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Arg 149 | Lys 696 | engineered mutation |
| Leu 233 | Ile 780 | engineered mutation |
| Lys 237 | Gln 784 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58801.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 434.1 | |
| All* | Total formula weight | 59235.5 |
