3G3D
Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 5-fluoro-6-azido-UMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Uridine 5'-monophosphate synthase | polymer | 312 | 34054.2 | 2 | UniProt (P11172) Pfam (PF00215) | Homo sapiens (Human) | UMP synthase |
| 2 | C, E (A, B) | 5-FLUORO-URIDINE-5'-MONOPHOSPHATE | non-polymer | 342.2 | 2 | Chemie (5FU) PubChem (150856) PubChem (415410) PubChem (46873925) PubChem (3080709) PubChem (57110488) PubChem (92160661) PubChem (172642480) | |||
| 3 | D, F, G (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) PubChem (753) | |||
| 4 | H (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 291 (UniProt: P11172)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Ser -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Arg -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68108.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1056.7 | |
| All* | Total formula weight | 69165.0 |
