3G1L

EthR from Mycobacterium tuberculosis in complex with compound BDM14744

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR	polymer	256	28124.4	1	UniProt (P96222) Pfam (PF00440) Pfam (PF21313) UniProt (by SIFTS) (P9WMC1)	Mycobacterium tuberculosis	Transcriptional regulator, TetR family
2	B (A)	3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole	non-polymer		239.2	1	Chemie (RF2)
3	C (A)	water	water		18.0	109	Chemie (HOH)

Sequence modifications

A: 1 - 216 (UniProt: P96222)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Met 217	-	expression tag
Gly 218	-	expression tag
Ser 219	-	expression tag
Ser 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag
His 226	-	expression tag
Ser 227	-	expression tag
Ser 228	-	expression tag
Gly 229	-	expression tag
Leu 230	-	expression tag
Val 231	-	expression tag
Pro 232	-	expression tag
Arg 233	-	expression tag
Gly 234	-	expression tag
Ser 235	-	expression tag
His 236	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	28124.4
Non-Polymers*	Number of molecules	1
	Total formula weight	239.2
All*	Total formula weight	28363.7

*Water molecules are not included.