3G0U
Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase | polymer | 367 | 39856.5 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (human) | DHOdehase, Dihydroorotate oxidase |
| 2 | B (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 3 | C (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 4 | D (A) | (2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide | non-polymer | 342.8 | 1 | Chemie (MDY) | |||
| 5 | E (A) | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39856.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 955.2 | |
| All* | Total formula weight | 40811.8 |
