3G01

Structure of GrC mutant E192R/E193G

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Granzyme C	polymer	227	25148.1	2	UniProt (P08882) Pfam (PF00089)	Mus musculus (mouse)	Cytotoxic cell protease 2, CCP2, B10
2	C, D (A, B)	water	water		18.0	28	Chemie (HOH)

Sequence modifications

A, B: 21 - 247 (UniProt: P08882)

PDB	External Database	Details
Arg 69	Ser 69	SEE REMARK 999
Arg 201	Glu 201	engineered mutation
Gly 202	Glu 202	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50296.1
All*	Total formula weight	50296.1

*Water molecules are not included.