3FZR
Crystal structure of PYK2 complexed with PF-431396
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein tyrosine kinase 2 beta | polymer | 277 | 32190.3 | 1 | UniProt (Q14289) Pfam (PF07714) | Homo sapiens (Human) | Focal adhesion kinase 2, FADK 2, Proline-rich tyrosine kinase 2, Cell adhesion kinase beta, CAK beta, Calcium-dependent tyrosine kinase, CADTK, Related adhesion focal tyrosine kinase, RAFTK |
| 2 | B (A) | N-methyl-N-{2-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]phenyl}methanesulfonamide | non-polymer | 506.5 | 1 | Chemie (3JZ) | |||
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D (A) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32190.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 601.5 | |
| All* | Total formula weight | 32791.8 |
