3FZD
Mutation of Asn28 disrupts the enzymatic activity and dimerization of SARS 3CLpro
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3C-like proteinase | polymer | 301 | 33301.0 | 1 | UniProt (P0C6U8) Pfam (PF05409) | SARS coronavirus (virus) | 3CL-PRO, 3CLp |
| 2 | B (A) | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence modifications
A: 3 - 301 (UniProt: P0C6U8)
| PDB | External Database | Details |
|---|---|---|
| Ala 28 | Asn 3268 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33301.0 | |
| All* | Total formula weight | 33301.0 |
