3FYJ
Crystal structure of an optimzied benzothiophene inhibitor bound to MAPKAP Kinase-2 (MK-2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | MAP kinase-activated protein kinase 2 | polymer | 327 | 37897.8 | 1 | UniProt (P49137) Pfam (PF00069) | Homo sapiens (human) | MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MK2 |
| 2 | B (X) | (10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one | non-polymer | 374.5 | 1 | Chemie (B97) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37897.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 374.5 | |
| All* | Total formula weight | 38272.2 |
