3FYJ

Crystal structure of an optimzied benzothiophene inhibitor bound to MAPKAP Kinase-2 (MK-2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	X	MAP kinase-activated protein kinase 2	polymer	327	37897.8	1	UniProt (P49137) Pfam (PF00069) In PDB	Homo sapiens (human)	MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MK2
2	X	(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one	non-polymer		374.5	1	Chemie (B97)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37897.8
Non-Polymers*	Number of molecules	1
	Total formula weight	374.5
All*	Total formula weight	38272.2

*Water molecules are not included.