3FXT

Crystal structure of the N-terminal domain of human NUDT6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Nucleoside diphosphate-linked moiety X motif 6	polymer	113	12647.2	8	UniProt (P53370) Pfam (PF18290)	Homo sapiens (Human)	Nudix motif 6, Protein GFG, GFG-1, Antisense basic fibroblast growth factor
2	I, J, K, L, M... (B, C, D, E, F)	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
3	O, P, Q, R, S... (A, B, C, D, E...)	water	water		18.0	354	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 45 - 134 (UniProt: P53370)

PDB	External Database	Details
Met 22	-	expression tag
His 23	-	expression tag
His 24	-	expression tag
His 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
Ser 29	-	expression tag
Ser 30	-	expression tag
Gly 31	-	expression tag
Val 32	-	expression tag
Asp 33	-	expression tag
Leu 34	-	expression tag
Gly 35	-	expression tag
Thr 36	-	expression tag
Glu 37	-	expression tag
Asn 38	-	expression tag
Leu 39	-	expression tag
Tyr 40	-	expression tag
Phe 41	-	expression tag
Gln 42	-	expression tag
Ser 43	-	expression tag
Met 44	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	101177.3
Non-Polymers*	Number of molecules	6
	Total formula weight	552.6
All*	Total formula weight	101729.9

*Water molecules are not included.