3FVF

The Crystal Structure of Prostasin Complexed with Camostat at 1.6 Angstroms Resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Prostasin	polymer	271	29608.0	1	UniProt (Q16651) Pfam (PF00089)	Homo sapiens (human)	Serine protease 8, Prostasin light chain, Prostasin heavy chain
2	B (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
3	C (B)	1-[4-(hydroxymethyl)phenyl]guanidine	non-polymer		165.2	1	Chemie (1JZ)
4	D, E (B)	DIMETHYL SULFOXIDE	non-polymer		78.1	2	Chemie (DMS)
5	F (B)	water	water		18.0	247	Chemie (HOH)

Sequence modifications

B: 16 - 262 (UniProt: Q16651)

PDB	External Database	Details
Ser 122	Cys 154	engineered mutation
Gln 127	Asn 159	engineered mutation
Ser 170	Cys 203	engineered mutation
His 263	-	expression tag
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Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29608.0
Non-Polymers*	Number of molecules	4
	Total formula weight	413.6
All*	Total formula weight	30021.6

*Water molecules are not included.