3FV8
JNK3 bound to piperazine amide inhibitor, SR2774.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitogen-activated protein kinase 10 | polymer | 355 | 41007.6 | 1 | UniProt (P53779) Pfam (PF00069) In PDB | Homo sapiens (human) | Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, MAP kinase p49 3F12 |
| 2 | A | 5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide | non-polymer | 422.7 | 1 | Chemie (JK3) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41007.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 733.0 | |
| All* | Total formula weight | 41740.6 |
