3FUG
Crystal Structure of the Retinoid X Receptor Ligand Binding Domain Bound to the Synthetic Agonist 3-[4-Hydroxy-3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-phenyl]acrylic Acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Retinoic acid receptor RXR-alpha | polymer | 240 | 26856.0 | 1 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (human) | Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1 |
| 2 | B (B) | Nuclear receptor coactivator 2 | polymer | 13 | 1535.9 | 1 | UniProt (Q15596) | NCoA-2, Transcriptional intermediary factor 2, hTIF2 | |
| 3 | C (A) | (2E)-3-[4-hydroxy-3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)phenyl]prop-2-enoic acid | non-polymer | 364.5 | 1 | Chemie (2E3) | |||
| 4 | D (A) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28391.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 364.5 | |
| All* | Total formula weight | 28756.4 |
