3FR5
N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte Fatty-Acid Binding Protein (A-FABP) inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Fatty acid-binding protein, adipocyte | polymer | 131 | 14608.7 | 1 | UniProt (P15090) Pfam (PF00061) In PDB | Homo sapiens (human) | A-FABP, AFABP, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, ALBP |
| 2 | A | 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid | non-polymer | 362.4 | 1 | Chemie (I4A) | |||
| 3 | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14608.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 362.4 | |
| All* | Total formula weight | 14971.1 |
