3FQX
Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 275 | 31854.2 | 1 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB | Homo sapiens (Human) | MHC class I antigen A*2 |
| 2 | B | Beta-2-microglobulin | polymer | 98 | 11635.0 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 3 | C | phospho-peptide 1097-1105 from insulin receptor substrate 2 (IRS2): RVA(Sep)PTSGV | polymer | 9 | 954.0 | 1 | UniProt (by SIFTS) (Q9Y4H2) In PDB | ||
| 4 | A, B | CADMIUM ION | non-polymer | 112.4 | 5 | Chemie (CD) | |||
| 5 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 413 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44443.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 794.9 | |
| All* | Total formula weight | 45238.0 |
