3FQU
Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 275 | 31854.2 | 1 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB | Homo sapiens (Human) | MHC class I antigen A*2 |
2 | B | Beta-2-microglobulin | polymer | 98 | 11635.0 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
3 | C | phospho-peptide 38-46 from cell division cycle 25b (CDC25b): GLLG(Sep)PVRA | polymer | 9 | 950.0 | 1 | UniProt (by SIFTS) (P30305) In PDB | ||
4 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
5 | A, B | CADMIUM ION | non-polymer | 112.4 | 6 | Chemie (CD) | |||
6 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
7 | water | water | 18.0 | 414 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 44439.2 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 1067.1 | |
All* | Total formula weight | 45506.4 |