3FQQ
Crystal structure of a novel dimeric form of HCV NS5A domain I protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Non-structural protein 5A | polymer | 177 | 19468.1 | 2 | UniProt (Q9WMX2) Pfam (PF08300) Pfam (PF08301) In PDB | Hepatitis C virus (isolate Con1) (HCV) | NS5A |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | A | 3-methyl-1-(2-methylpropyl)butyl 4-O-beta-L-gulopyranosyl-beta-D-glucopyranoside | non-polymer | 468.5 | 1 | Chemie (0BD) | |||
| 5 | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence modifications
A, B: 33 - 202 (UniProt: Q9WMX2)
| PDB | External Database | Details |
|---|---|---|
| Ala 31 | - | expression tag |
| Leu 32 | - | expression tag |
| Asp 203 | - | expression tag |
| Asp 204 | - | expression tag |
| Asp 205 | - | expression tag |
| Asp 206 | - | expression tag |
| Lys 207 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38936.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 691.4 | |
| All* | Total formula weight | 39627.6 |
