3FPM
Crystal Structure of a Squarate Inhibitor bound to MAPKAP Kinase-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | MAP kinase-activated protein kinase 2 | polymer | 325 | 37652.5 | 1 | UniProt (P49137) Pfam (PF00069) In PDB | Homo sapiens (human) | MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MK2 |
| 2 | A | 3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione | non-polymer | 293.3 | 1 | Chemie (793) |
Sequence modifications
A: 41 - 364 (UniProt: P49137)
| PDB | External Database | Details |
|---|---|---|
| Met 40 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37652.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 293.3 | |
| All* | Total formula weight | 37945.8 |
