3FPD
G9a-like protein lysine methyltransferase inhibition by BIX-01294
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 | polymer | 261 | 30232.4 | 2 | UniProt (Q9H9B1) Pfam (PF05033) Pfam (PF00856) In PDB | Homo sapiens (human) | Histone H3-K9 methyltransferase 5, H3-K9-HMTase 5, Euchromatic histone-lysine N-methyltransferase 1, Eu-HMTase1, G9a-like protein 1, GLP1, Lysine N-methyltransferase 1D |
| 2 | A, B | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 3 | A, B | N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine | non-polymer | 490.6 | 2 | Chemie (Q4A) | |||
| 4 | A, B | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 5 | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60464.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2273.4 | |
| All* | Total formula weight | 62738.1 |
