3FO7
Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site
Replaces: 2DV8Replaces: 1TI0Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Phospholipase A2 VRV-PL-VIIIa | polymer | 121 | 13629.8 | 1 | Pfam (PF00068) UniProt (by SIFTS) (P59071) In PDB | Daboia russelli pulchella | Phosphatidylcholine 2-acylhydrolase, DPLA2, P1 |
2 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
3 | A | INDOMETHACIN | non-polymer | 357.8 | 1 | Chemie (IMN) | |||
4 | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 13629.8 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 742.0 | |
All* | Total formula weight | 14371.8 |