3FO7
Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site
Replaces: 2DV8Replaces: 1TI0Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phospholipase A2 VRV-PL-VIIIa | polymer | 121 | 13629.8 | 1 | Pfam (PF00068) UniProt (by SIFTS) (P59071) | Daboia russelli pulchella | Phosphatidylcholine 2-acylhydrolase, DPLA2, P1 |
| 2 | B, C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F (A) | INDOMETHACIN | non-polymer | 357.8 | 1 | Chemie (IMN) | |||
| 4 | G (A) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13629.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 742.0 | |
| All* | Total formula weight | 14371.8 |
