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3FO7

Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site

Replaces:  2DV8Replaces:  1TI0
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1APhospholipase A2 VRV-PL-VIIIapolymer12113629.81Pfam (PF00068)
UniProt (by SIFTS) (P59071)
In PDB
Daboia russelli pulchellaPhosphatidylcholine 2-acylhydrolase, DPLA2, P1
2ASULFATE IONnon-polymer96.14Chemie (SO4)
3AINDOMETHACINnon-polymer357.81Chemie (IMN)
4waterwater18.0224Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight13629.8
Non-Polymers*Number of molecules5
Total formula weight742.0
All*Total formula weight14371.8
*Water molecules are not included.

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PDB entries from 2024-07-24

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