3FMI

Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase complexed with 7-Keto 8-aminopelargonic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Dethiobiotin synthetase	polymer	251	25331.9	4	UniProt (O06620) Pfam (PF13500) UniProt (by SIFTS) (P9WPQ5)	Mycobacterium tuberculosis	DTB synthetase, DTBS
2	E, H, I, K (A, B, C, D)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	F, G, J (A, B, C)	7-KETO-8-AMINOPELARGONIC ACID	non-polymer		187.2	3	Chemie (KAP)
4	L, M, N, O (A, B, C, D)	water	water		18.0	210	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 226 (UniProt: O06620)

PDB	External Database	Details
Met -24	-	expression tag
Gly -23	-	expression tag
Ser -22	-	expression tag
Ser -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Leu -11	-	expression tag
Gln -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	101327.6
Non-Polymers*	Number of molecules	7
	Total formula weight	946.0
All*	Total formula weight	102273.5

*Water molecules are not included.