3FL7

Crystal structure of the human ephrin A2 ectodomain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ephrin receptor	polymer	536	59218.9	1	UniProt (Q8N3Z2) Pfam (PF01404) Pfam (PF00041) UniProt (by SIFTS) (P29317) In PDB	Homo sapiens (Human)
2	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
3	A	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5		water	water		18.0	46	Chemie (HOH)

Sequence modifications

A: 23 - 531 (UniProt: Q8N3Z2)

PDB	External Database	Details
Ala -4	-	expression tag
Ala -3	-	expression tag
Pro -2	-	expression tag
Glu -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
Asp 6	-	expression tag
Tyr 7	-	expression tag
Asp 8	-	expression tag
Ile 9	-	expression tag
Pro 10	-	expression tag
Thr 11	-	expression tag
Thr 12	-	expression tag
Glu 13	-	expression tag
Asn 14	-	expression tag
Leu 15	-	expression tag
Tyr 16	-	expression tag
Phe 17	-	expression tag
Gln 18	-	expression tag
Gly 19	-	expression tag
Ala 20	-	expression tag
Met 21	-	expression tag
Asp 22	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	59218.9
Non-Polymers*	Number of molecules	5
	Total formula weight	350.6
All*	Total formula weight	59569.5

*Water molecules are not included.