3FJK

Crystal structure of A66C mutant of Human acidic fibroblast growth factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Heparin-binding growth factor 1	polymer	146	16718.8	4	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (human)	HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
2	B, C	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	B, D	FORMIC ACID	non-polymer		46.0	2	Chemie (FMT)
4		water	water		18.0	178	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Cys 66	Ala 81	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	66875.2
Non-Polymers*	Number of molecules	4
	Total formula weight	284.2
All*	Total formula weight	67159.4

*Water molecules are not included.