3FJJ

Crystal structure of C83V mutant of Human acidic fibroblast growth factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Heparin-binding growth factor 1	polymer	146	16682.7	2	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (human)	HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
2	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	A, B	FORMIC ACID	non-polymer		46.0	6	Chemie (FMT)
4		water	water		18.0	275	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Val 83	Cys 98	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33365.5
Non-Polymers*	Number of molecules	7
	Total formula weight	372.2
All*	Total formula weight	33737.7

*Water molecules are not included.