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3FJI

Crystal structure of K12V/C83I/C117V mutant of Human acidic fibroblast growth factor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DHeparin-binding growth factor 1polymer14616662.74UniProt (P05230)
Pfam (PF00167)
In PDB
Homo sapiens (human)HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
2A, DSULFATE IONnon-polymer96.12Chemie (SO4)
3waterwater18.0106Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 140 (UniProt: P05230)
PDBExternal DatabaseDetails
His 1-expression tag
His 1-expression tag
His 1-expression tag
His 1-expression tag
His 1-expression tag
His 1-expression tag
Val 12Lys 27engineered mutation
Ile 83Cys 98engineered mutation
Val 117Cys 132engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight66650.8
Non-Polymers*Number of molecules2
Total formula weight192.1
All*Total formula weight66842.9
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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