3FJA

Crystal structure of F132W mutant of Human acidic fibroblast growth factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heparin-binding growth factor 1	polymer	146	16725.8	2	UniProt (P05230) Pfam (PF00167)	Homo sapiens (human)	HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
2	C, D, E, F (A, B)	FORMIC ACID	non-polymer		46.0	4	Chemie (FMT)
3	G, H (A, B)	water	water		18.0	235	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Trp 132	Phe 147	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33451.6
Non-Polymers*	Number of molecules	4
	Total formula weight	184.1
All*	Total formula weight	33635.7

*Water molecules are not included.