3FJ9
Crystal structure of F85W mutant of Human acidic fibroblast growth factor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Heparin-binding growth factor 1 | polymer | 146 | 16725.8 | 2 | UniProt (P05230) Pfam (PF00167) In PDB | Homo sapiens (human) | HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta |
2 | A, B | FORMIC ACID | non-polymer | 46.0 | 5 | Chemie (FMT) | |||
3 | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 140 (UniProt: P05230)
PDB | External Database | Details |
---|---|---|
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
Trp 85 | Phe 100 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 33451.6 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 230.1 | |
All* | Total formula weight | 33681.7 |