3FJ8

Crystal structure of C117I mutant of Human acidic fibroblast growth factor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Heparin-binding growth factor 1	polymer	146	16696.8	2	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (human)	HBGF-1, Acidic fibroblast growth factor, aFGF, Beta-endothelial cell growth factor, ECGF-beta
2	A, B	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3		water	water		18.0	187	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Ile 117	Cys 132	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33393.5
Non-Polymers*	Number of molecules	3
	Total formula weight	288.2
All*	Total formula weight	33681.7

*Water molecules are not included.