3FI3
Crystal structure of JNK3 with indazole inhibitor, SR-3737
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 10 | polymer | 364 | 42235.9 | 1 | UniProt (P53779) Pfam (PF00069) | Homo sapiens (Human) | Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, MAP kinase p49 3F12 |
| 2 | B (A) | 3-{5-[(2-fluorophenyl)amino]-1H-indazol-1-yl}-N-(3,4,5-trimethoxyphenyl)benzamide | non-polymer | 512.5 | 1 | Chemie (JK2) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (A) | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42235.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 636.7 | |
| All* | Total formula weight | 42872.6 |
